Acute Myeloid Leukemia | Tumor

CURE’s acute myeloid leukemia page features the latest cancer news and updates on acute myeloid leukemia. Through articles, videos, podcasts, and more, CURE brings readers the insights of experts, cancer survivors, patients, and advocates to ensure everyone is up to date in acute myeloid leukemia.

FDA Stops Study of Novel Blood Cancer Drug

August 23rd 2022

The Food and Drug Administration put a full clinical hold on a study of the novel drug FHD-286 in patients with acute myelogenous leukemia and myelodysplastic syndrome after study data showed an increase in a potentially fatal side effect.

First Patient Receives Investigational Cancer Drug-Combination for Relapsed/Refractory Acute Myeloid Leukemia

August 22nd 2022

Adding the investigational cancer drug lanraplenib to Xospata, if found to be effective, may broaden treatment options for patients with relapsed/refractory FLT3-mutated acute myeloid leukemia.

Trial to Compare Safety and Efficacy of Novel Cell Therapy to Standard of Care in Patients With Rare Blood Cancers

August 3rd 2022

Enrollment has begun on a phase 3 clinical trial assessing the safety and efficacy of an investigational cell therapy in patients with acute myeloid leukemia, acute lymphocytic leukemia and myelodysplastic syndromes.

Outcomes Are Best When Patients With Cancer Are as Aware of Their Disease as Their Provider, Expert Says

August 2nd 2022

Patients with cancer are encouraged to learn more about their disease from evidenced-based sources and not “Dr. Google.”

Novel Drug-Chemotherapy Combo After Stem Cell Transplant Associated With ‘Favorable Survival Outcomes’ in Group of Rare Blood Cancers

July 26th 2022

The findings support future studies of assessing the safety and efficacy of the novel drug-chemotherapy combination as a maintenance strategy following stem cell transplantation across a range of blood cancers, according to the study authors.

Tibsovo Plus Vidaza Is Beneficial for Patients With IDH1-Mutant Acute Myeloid Leukemia

June 4th 2022

Tibsovo plus Vidaza led to survival benefit for patients with IDH1-mutant acute myeloid leukemia, according to findings from the AGILE clinical trial.

Patient With Leukemia Subtype Undergoes Stem Cell Transplant After Receiving Novel Monotherapy in Early-Phase Trial

April 1st 2022

Treatment with a novel monotherapy in a patient with relapsed/refractory acute myeloid leukemia was effective enough that a successful, as indicated by a significant reduction in bone marrow blasts, stem cell transplant was performed.

Trial Initiated to Study Protein-Inhibiting Treatment Option for Patients With Acute Leukemia

February 17th 2022

A trial to examine BMF-219 in patients with relapsed or refractory acute leukemias has begun recruiting patients across multiple U.S. states.

FDA Halts Several Studies Examining Magrolimab-Onureg Combo Across Multiple Cancer Types Due to Serious Side Effects

January 28th 2022

All clinical trials investigating the combination of magrolimab and the chemotherapy Onureg have been paused due to unforeseen serious side effects experienced by patients with various blood cancers receiving the treatment.

Trial Underway for Potential First Treatment Option of Newly Diagnosed NPM1-Mutant AML

January 12th 2022

A phase 3 trial has begun to examine entospletinib, a selective inhibitor, as a treatment for patients with newly diagnosed NPM1-mutated acute myeloid leukemia.

mRNA COVID-19 Vaccination Sparks Strong Antibody Response in Patients With AML and MDS

December 13th 2021

Most patients with acute myeloid leukemia and myelodysplastic syndrome achieved strong antibody responses to COVID-19 vaccination, according to recent study results.

Kymriah May Be Safe and Effective in Children and Young Adults With Acute Lymphoblastic Leukemia Subtype

December 12th 2021

The immunotherapy Kymriah offered similar benefits in patients younger than and older than 18 years with relapsed/refractory B-cell acute lymphoblastic leukemia.

Cancer Clinical Trial Enrollment Is Low in the US, and Patient Depression and Anxiety May Play a Role

December 12th 2021

Researchers found that depression and anxiety may skew patient perceptions of participating in blood cancer clinical trials, thus contributing to low enrollment throughout the United States.

Phase 2 Trial Initiated for Second Line Treatment of AML and MDS

November 18th 2021

A phase 2 trial of aspacytarabine (BST-236) was initiated in patients with AML and MDS.

New Drug Disappoints for Pancreatic Cancer and AML Treatment

October 29th 2021

Study results showed that CPI-613 did not improve survival in patients with metastatic adenocarcinoma of the pancreas.

‘Mommy Doesn’t Have Hair Right Now’: Receiving a Cancer Diagnosis as a Young Mother

October 28th 2021

On this episode of the “Cancer Horizons” podcast, CURE® contributor Amanda Ferraro describes what it was like to receive a cancer diagnosis at 28 years old with a 3-year-old child and discusses the importance of mental health for cancer survivors.

Better Days Ahead for Patients With AML

October 20th 2021

An abundance of clinical trials is giving patients with acute myeloid leukemia (AML) hope for a better future.

Third Dose of COVID-19 Vaccine May Increase Protection in Immunocompromised Patients

August 19th 2021

Patients who are immunocompromised, such as patients with blood cancers, may get the boosted immunity needed to reduce their risk for contracting COVID-19 and hospitalization for compilations related to the virus.

Treatment of AML in Older Patients Almost At ‘The Holy Grail’

August 14th 2021

“We are fortunate now to live in an era where we have nine new drugs approved (for AML) just in the last five years,” says an expert from The University of Texas MD Anderson Cancer Center.

Educated Patients Are The ‘Key To The Success’ Of Their Cancer Therapy

August 11th 2021

“More and more (patients and physicians) need to work together in partnership throughout the cancer journey in order to optimize and make the journey the best possible that we can for every single patient,” says an expert from the Roswell Park Comprehensive Cancer Center.

Paying it Forward in the Flow

July 16th 2021

A woman shares the story of her journey with multiple cancer types, including the same one that her mother died from.

Palliative Care Improves Coping in Patients with A Certain Type of Leukemia

June 9th 2021

Introducing integrated palliative care to patients with a certain type of leukemia was shown to facilitate active coping strategies, which could improve a patient’s quality of life.

Potential Genetic Target Found for Treating Pediatric Leukemia

May 24th 2021

Scientists have identified a potentially valuable genetic target in children with acute myeloid leukemia that could lead to further studies in immunotherapy drugs for the disease.

Childhood Down Syndrome and Acute Myeloid Leukemia Association ‘Greater Than Previously Reported’

May 12th 2021

An analysis of more than 3.5 million children born between January 1996 and December 2016 demonstrated a stronger association between Down syndrome and acute myeloid leukemia risk than has been previously reported.

Early Study Results Show Novel Therapy Safe and Effective in Relapsed/Refractory Acute Myeloid Leukemia

May 11th 2021

Treatment with a novel therapy as a single agent, or in combination with Venclexta, demonstrated a manageable safety profile and antileukemic effects in patients with relapsed/refractory acute myeloid leukemia. The study authors, however, note that more research is needed.

Venclexta With a Hypomethylating Agent Shows Promise for Patients with Acute Myeloid Leukemia

May 6th 2021

Compared to a hypomethylating agent alone, combining the agent with Venclexta improved complete remission rates in patients with blast-phase myeloproliferative neoplasm.

Why the COVID-19 Vaccine is Important for Patients with Blood Cancers

April 27th 2021

Patients with blood cancers are at a much higher risk of complications if they contract COVID-19, says an expert from the Leukemia & Lymphoma Society (LLS).

Post-Traumatic Stress Disorder Prevalent in Patients with Acute Myeloid Leukemia

April 21st 2021

Patients with acute myeloid leukemia experience post-traumatic stress disorder symptoms including intrusion, avoidance and hypervigilance one month after diagnosis.

FDA Approves Expanded Label of Vyxeos to Include Pediatric Patients with Secondary AML

March 31st 2021

The agency granted approval to the revised label of Vyxeos to now include treatment for newly diagnosed therapy-related acute myeloid leukemia or disease with myelodysplasia-related changes in pediatric patients aged 1 and older.

‘Attitude is Everything’ When Dealing with Cancer

February 11th 2021

This week on the “CURE Talks Cancer” podcast, we spoke with Nicole Schulz, who was diagnosed with acute myeloid leukemia at the age of 14, about how her life changed as a result of her treatment and why she now lives life to the fullest.

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